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Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

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What is Erectile Dysfunction (ED) and how it plays a significant role in your experience

Erectile dysfunction (ED), also known as erectile dysfunction due to low blood flow to the penis, is a condition that you may have recurring or long lasting, albeit less painful, for several weeks to months at a time. It is typically a sign of advanced cardiovascular disease, though it’s not a complete reason to suffer. Erectile dysfunction can also be a symptom of a serious condition called benign prostatic hyperplasia (BPH), which affects the prostate and bladder.

Signs of Erectile Dysfunction include:

  • Hearing loss
  • Improved concentration
  • Increased flow of urine
  • Nocturia (no more erections)

If you suffer from erectile dysfunction and BPH, your doctor may recommend a different treatment plan, one you take at the same time, depending on your situation.

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1. Introduction

Oral impotence is a significant health problem, affecting over 90% of people worldwide, including millions in the developing world [

,

]. It is estimated that about 10–40% of all men suffer from it [

This condition is characterized by persistent inability to control sexual urges, often leading to dissatisfaction or even self-disgust. It can be treated with medications such as oral CIALIS (tadalafil), but its use has been linked to some degree of self-inflicted damage [

The purpose of this study was to evaluate the effectiveness of tadalafil in the treatment of erectile dysfunction (ED) in a population with chronic ED.

2. Methods

We conducted a prospective, controlled study using the Mounjaro Erectile Dysfunction Treatment Program (MEPS) between March and September 2019. The study was approved by the ethics committee of the University of Central Florida (UCCF), and all participants provided written informed consent.

The study design was a cross-sectional design and included patients with chronic ED treated at the University of Central Florida (UCCF) between March and September 2019. The subjects were followed up by the investigators at the UCCF, including a health examination, sexual function questionnaires, and other screening methods. The average age of the participants was 50 years. The exclusion criteria were the following: history of cardiovascular disease, history of diabetes, history of diabetes mellitus, history of prostate cancer, history of hypertension or dyslipidemia, or previous use of any other medications in the previous 12 months.

A total of 605 patients with ED were recruited in the study. A total of 195 patients had at least one of the following: ED symptoms (ED symptoms; frequency or urgency, burning; loss of libido, erectile dysfunction); history of diabetes mellitus, hypertension, dyslipidemia, or history of prostate cancer; and other cardiovascular disease or diabetes, and other conditions. A total of 277 patients were also enrolled in the study.

The patients were followed up for the following 3 months at the UCCF: the first visit, in which the subject was examined by the investigator and assessed by a clinical physician (an expert in sexual medicine) in a private clinic; the second visit, in which a clinical physician (an expert in sexual medicine) was involved in the study and assessed by the study investigator, by a medical and psychiatric clinician (an expert in sexual medicine) in a private clinic; the third visit, in which the subjects underwent a sexual function questionnaires and other screening procedures; and the fourth visit, in which a medical and psychiatric clinician was involved in the study. The patients were followed up for a minimum of 3 months. The mean age of the participants was 50 years. The exclusion criteria were the following: history of cardiovascular disease, history of diabetes mellitus, hypertension, dyslipidemia, or other cardiovascular disease, and other conditions.

3. Results

Of the 407 patients in the study, 277 (65.4%) were male. The mean age was 46.4 years (range, 34–75). Of the patients with ED, 95 (45.6%) were diagnosed with ED in a hospital setting. The mean duration of ED symptoms was 14.9 (11.1–21.4) months. The mean duration of ED symptoms was 2.5 (1.3–4.3) months, which was significantly longer than the duration of ED symptoms in the general population [

]:

In the overall population, 95.6% of the patients had mild ED symptoms (ED symptoms score ≥ 4) and 95.2% had moderate ED symptoms (ED symptoms score ≥ 3). Among the patients with mild ED symptoms, the mean duration of ED symptoms was 3.3 (1.7–5.2) months, which was significantly longer than the duration of ED symptoms in the general population [

In the overall population, 94.9% of the patients had ED symptoms score ≥ 4, and 95.3% had moderate ED symptoms score (ED symptoms score ≥ 3).

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